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Article

Dystroglycan is required for proper retinal layering.

Developmental biology - 15 Feb 2006

Lunardi Andrea, Cremisi Federico, Dente Luciana

Abstract excerpt

Dystroglycan (DG) is a transmembrane receptor linking the extracellular matrix to the internal cytoskeleton. Its structural function has been mainly characterized in muscle fibers, but DG plays signaling and developmental roles also in different tissues and cell types. We have investigated the effects of dystroglycan depletion during eye development of Xenopus laevis. We have injected a specific morpholino (Mo)...

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Identifiers

PMID: 16406325
DOI: 10.1016/j.ydbio.2005.11.044

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Dystroglycan is required for proper retinal layering.PMID 16406325Read ↗

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Genetic modifier screens reveal new components that interact with the Drosophila dystroglycan-dystrophin complex.Semantic proximity Read ↗

Genetic aspects of embryonic eye development in vertebrates.Semantic proximity Read ↗

A missense mutation (C667F) in β-dystroglycan results in reduced dystroglycan protein levels leading to myopathy and destabilization of the blood-brain and blood-retinal barrier protein networkSemantic proximity Read ↗

The missense mutation C667F in murine β-dystroglycan causes embryonic lethality, myopathy and blood-brain barrier destabilization.Semantic proximity Read ↗

Dystroglycan is required for polarizing the epithelial cells and the oocyte in Drosophila.Semantic proximity Read ↗

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Dystroglycan Is Essential for Early Embryonic Development: Disruption of Reichert's Membrane in Dag1-Null MiceSemantic proximity Read ↗

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