Article
The zebrafish Pard3 ortholog is required for separation of the eye fields and retinal lamination.
Developmental biology - 1 May 2004
Wei Xiangyun, Cheng Yan, Luo Yiying, Shi Xiaohai, Nelson Scott, Hyde David R
Abstract excerpt
The vertebrate retina develops from a sheet of neuroepithelial cells. Because adherens and tight junctions are critical for epithelial and neuronal differentiation in a variety of eukaryotic systems, we examined the role of Par-3, a PDZ scaffold protein that is critical in cellular membrane junction formation. We cloned the zebrafish Par-3 ortholog (pard3), which encodes two Pard3 proteins (150 and 180 kDa) that...
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