Article
Eye defects in receptor protein-tyrosine phosphatase alpha knock-down zebrafish.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Mar 2002
van der Sar Astrid M, Zivković Danica, den Hertog Jeroen
Abstract excerpt
Receptor protein-tyrosine phosphatase alpha (RPTP alpha) is highly expressed in the developing retina of different species, but little is known about its function there. Here, we report that injection of antisense morpholinos in zebrafish embryos reduced RPTP alpha expression to almost nondetectable levels up to 3 days postfertilization (dpf). RPTP alpha was detectable again from 4 dpf onward. RPTP alpha...
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