Article
Origin and evolution of acrocentric chromosomes in human and great apes
2025-12-23
Abstract excerpt
The short arms of human acrocentric chromosomes are characterized by nucleolar organizer regions essential for ribosome biogenesis, but their highly repetitive nature has hindered genomic analysis. Leveraging the recently completed genomes of all major ape lineages, we identified recurrent features of their acrocentrics, including enriched repeat classes, centromere repositioning by whole-arm inversion, interchrom...
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Identifiers and source
- Literature Corpus work
- b8ae581b-d119-52c2-bd44-d23e067723fe
- DOI
- 10.64898/2025.12.22.696095