Article
Expansion of CD19(hi)CD21(lo/neg) B cells in common variable immunodeficiency (CVID) patients with autoimmune cytopenia.
Immunobiology - 1 Dec 2002
Warnatz Klaus, Wehr Claudia, Dräger Ruth, Schmidt Sigune, Eibel Hermann, Schlesier Michael, Peter Hans-Hartmut
Abstract excerpt
Common variable immunodeficiency (CVID) is characterized by a severe hypogammaglobulinemia. While the clinical picture is dominated by recurrent respiratory and gastrointestinal infections, a subgroup of up to 30% of the patients develops additional autoimmune phenomena, including thrombocytopenia and autoimmune hemolytic anemia. So far no classification allowed a prediction of the coincidence of immunodeficiency...
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