Article
Disturbed peripheral B lymphocyte homeostasis in systemic lupus erythematosus.
Journal of immunology (Baltimore, Md. : 1950) - 15 Nov 2000
Odendahl M, Jacobi A, Hansen A, Feist E, Hiepe F, Burmester G R, Lipsky P E, Radbruch A, Dörner T
Abstract excerpt
In patients with active systemic lupus erythematosus (SLE), a marked B lymphocytopenia was identified that affected CD19(+)/CD27(-) naive B cells more than CD19(+)/CD27(+) memory B cells, leading to a relative predominance of CD27-expressing peripheral B cells. CD27(high)/CD38(+)/CD19(dim)/surfac...
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