Regression to the truth: replication of association in pharmacogenetic studies.

Abstract excerpt

Large, prospective trials demonstrating the value of genotyping in patient management will be required to support the introduction of pharmacogenetics into routine medical practice. However, such studies will be costly and can be justified only if there is a reproducible association between genotype and a clinically relevant phenotype. Unfortunately, non-replication is prevalent among genetic association studies....

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genotype
• Share to Pharmaceutical Preparations
• Share to Pharmacogenetics