Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Confounding in genetic association studies and its solutions.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2008

Hu Donglei, Ziv Elad

Abstract excerpt

An association study can be used to investigate how individuals with unique genetic variants respond to a drug treatment. In an association study, individuals may come from different ethnic groups or an admixed population. The heterogeneity of genetic backgrounds among individuals in association studies may lead to false-positive or false-negative results. Confounding caused by population structure and recent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biotransformation
Share to Confounding Factors, Epidemiologic
Share to Epidemiologic Research Design

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetics, Population

Share to Models, Genetic

Share to Patient Selection

Share to Pharmacogenetics

Share to Reproducibility of Results

Source

Identifiers

PMID: 18370229
DOI: 10.1007/978-1-59745-205-2_3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Confounding in genetic association studies and its solutions.PMID 18370229Read ↗

Population Stratification in Genetic Association Studies.Semantic proximity Read ↗

Population stratification and spurious allelic association.Semantic proximity Read ↗

Accounting for ancestry: population substructure and genome-wide association studies.Semantic proximity Read ↗

Control of confounding of genetic associations in stratified populations.Semantic proximity Read ↗

Obstacles and opportunities in meta-analysis of genetic association studies.Semantic proximity Read ↗

Human population structure and genetic association studies.Semantic proximity Read ↗

Adjusting for confounding due to population admixture when estimating the effect of candidate genes on quantitative traits.Semantic proximity Read ↗

Statistical issues in gene association studies.Semantic proximity Read ↗

Overdispersion of allele frequency differences between populations: implications for meta-analyses of genotypic disease associations.Semantic proximity Read ↗

Case-control studies in the genomic era: a clinician's guide.Semantic proximity Read ↗

Correction of population stratification in large multi-ethnic association studies.Semantic proximity Read ↗

Detecting association in a case-control study while correcting for population stratification.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.