Article
Association of thymidylate synthase 5'-UTR 28bp tandem repeat and serine hydroxymethyltransfarase C1420T polymorphisms with susceptibility to acute leukemia.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014
Dunna Nageswara Rao, Naushad Shaik Mohammad, Vuree Sugunakar, Anuradha Cingeetham, Sailaja Kagita, Surekha Damineni, Rao Digumarti Raghunadha, Vishnupriya Satti
Abstract excerpt
BACKGROUND: The current study was aimed to elucidate the association of thymidylate synthase (TYMS) 5'- UTR 28bp tandem repeat and cytosolic serine hydroxymethyltransferase (cSHMT) C1420T polymorphisms with acute leukemia in South Indian subjects. A total of 812 subjects [523 healthy controls, 148 acute lymphoblastic leukemia (ALL) cases and 141 acute myeloid leukemia (AML) cases] were screened for TYMS 5'-UTR...
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