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Article

Helicobacter pylori CagA containing ITAM-like sequences localized to lipid rafts negatively regulates VacA-induced signaling in vivo.

Helicobacter - 1 Feb 2003

Asahi Momoyo, Tanaka Yukie, Izumi Toshimasa, Ito Yoshiyuki, Naiki Hironobu, Kersulyte Dangeruta, Tsujikawa Kazutake, Saito Masakazu, Sada Kiyonao, Yanagi Shigeru, Fujikawa Akihiro, Noda Masaharu, Itokawa Yoshinori

Abstract excerpt

BACKGROUND: Helicobacter pylori CagA is injected into the host cell and tyrosine-phosphorylated. We examined tyrosine-phosphorylation sites of CagA, as well as the function of CagA proteins in vivo and in vitro. METHODS: After proteolytic digestion of CagA with lysyl endopeptidase, CagA tyrosine-phosphorylation sites were determined using quadropolar time-of-flight (Q-TOF) mass spectrometry analysis. Specific...

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Identifiers

PMID: 12603611
DOI: 10.1046/j.1523-5378.2003.00118.x

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GIT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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