Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Exploiting the enzymatic recognition of an unnatural base pair to develop a universal genetic analysis system.

Clinical chemistry - 1 Mar 2003

Moser Michael J, Marshall David J, Grenier Jennifer K, Kieffer Collin D, Killeen Anthony A, Ptacin Jerod L, Richmond Craig S, Roesch Eric B, Scherrer Christopher W, Sherrill Christopher B, Van Hout Cris V, Zanton Sara J, Prudent James R

Abstract excerpt

BACKGROUND: With the invention of the DNA chip, genome-wide analysis is now a reality. Unfortunately, solid-phase detection systems such as the DNA chip suffer from a narrow range in quantification and sensitivity. Today the best methodology for sensitive, wide dynamic range quantification and ge...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actins
Share to Base Composition

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Energy Transfer

Share to Factor V

Share to Nucleic Acids

Share to Oligonucleotide Probes

Share to Prothrombin

Share to RNA, Ribosomal, 18S

Source

Identifiers

PMID: 12600952
DOI: 10.1373/49.3.407

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12600952-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Exploiting the enzymatic recognition of an unnatural base pair to develop a universal genetic analysis system.PMID 12600952Read ↗

A universal approach for mutation identification with a DNA probe-enzyme combination platform.Semantic proximity Read ↗

PCR-Based Detection Methods for Single-Nucleotide Polymorphism or Mutation: Real-Time PCR and Its Substantial Contribution Toward Technological Refinement.Semantic proximity Read ↗

Modified Taq DNA Polymerase for Allele-Specific Ultra-Sensitive Detection of Genetic Variants.Semantic proximity Read ↗

Antiprimer quenching-based real-time PCR and its application to the analysis of clinical cancer samples.Semantic proximity Read ↗

Programmable One-Pot Enzymatic Reaction for Direct Fluorescence Detection of Ultralow-Abundance Mutations in the DNA Duplex.Semantic proximity Read ↗

Tuning the specificity of DNA probes using bulge-loops for low-abundance SNV detection.Semantic proximity Read ↗

Custom-Designed Probes for the Accurate Determination of Epidermal Growth Factor Receptor Mutations and Their Allelic Configuration.Semantic proximity Read ↗

Evolving methods for single nucleotide polymorphism detection: Factor V Leiden mutation detection.Semantic proximity Read ↗

Genotyping of single-nucleotide polymorphisms by high-resolution melting of small amplicons.Semantic proximity Read ↗

Locked nucleic acid (LNA) single nucleotide polymorphism (SNP) genotype analysis and validation using real-time PCR.Semantic proximity Read ↗

High-throughput SNP genotyping by allele-specific PCR with universal energy-transfer-labeled primers.Semantic proximity Read ↗

Detection of the factor V Leiden mutation by a modified photo-cross-linking oligonucleotide hybridization assay.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.