Article
Brief report: the IL23R nonsynonymous polymorphism rs11209026 is associated with radiographic sacroiliitis in spondyloarthritis.
Arthritis and rheumatism - 1 Oct 2013
Kadi Amir, Costantino Félicie, Izac Brigitte, Leboime Ariane, Said-Nahal Roula, Garchon Henri-Jean, Chiocchia Gilles, Breban Maxime
Abstract excerpt
OBJECTIVE: Spondyloarthritis (SpA) is a group of inflammatory articular disorders sharing a genetic background. The nonsynonymous single-nucleotide polymorphism (SNP) rs11209026 (Arg381Gln) in the IL23R gene has reproducibly been shown to be associated with ankylosing spondylitis (AS). We undertook this study to examine the association between rs11209026 and SpA as a whole, with particular attention devoted to...
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