Article
Interleukin-10 promoter polymorphism in psoriasis.
The Journal of investigative dermatology - 1 Jun 2001
Asadullah K, Eskdale J, Wiese A, Gallagher G, Friedrich M, Sterry W
Abstract excerpt
Beneficial effects of interleukin-10 therapy and lower endogenous interleukin-10 formation compared with atopic dermatitis and cutaneous T cell lymphomas indicated that interleukin-10 is a key cytokine in psoriasis. The interleukin-10 promoter is highly polymorphic, with two informative microsatellites, interleukin-10.G and interleukin-10.R. In order to understand whether interleukin-10 itself is a predisposing...
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