Article
[Genetic monitoring of tuberculous infection severity in mice with complementary inheritance of resistance].
Problemy tuberkuleza - 1 Jan 2002
Radaeva T V, Nikonenko B V, Apt A S
Abstract excerpt
When infected with a high dose of Mycobacterium tuberculosis H37Rv intravenously, 1/St and C57BL/6 inbred mice display a similarly high degree of the severity of progressive disease characterized by short-term survival rates and a rapid body weight loss. Noteworthy, F1 hybrids between these two strains are exceptionally resistant to M. tuberculosis-triggered disease and survive about 4-fold longer than the either...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.