Article
Severity of tuberculosis in mice is linked to distal chromosome 3 and proximal chromosome 9.
The Journal of infectious diseases - 1 Jul 1999
Lavebratt C, Apt A S, Nikonenko B V, Schalling M, Schurr E
Abstract excerpt
Genetic factors play a role in host response to infection with Mycobacterium tuberculosis, the number one infectious killer worldwide. Mice of the inbred strains I/St and A/Sn show significant differences in disease severity after intravenous injection of a lethal dose of the virulent human isola...
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