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Article

Genetic architecture of tuberculosis resistance in a mouse model of infection.

Genes and immunity - 1 Apr 2006

Yan B-S, Kirby A, Shebzukhov Y V, Daly M J, Kramnik I

Abstract excerpt

Tuberculosis remains a significant public health problem: one-third of the human population is infected with virulent Mycobacterium tuberculosis (MTB) and 10% of those are at risk of developing tuberculosis during their lifetime. In both humans and experimental animal models, genetic variation among infected individuals contributes to the outcome of infection. However, in immunocompetent individuals (the majority...

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PMID: 16452998
DOI: 10.1038/sj.gene.6364288

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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