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Article

Molecular characterization of new polymorphisms at the beta2, alpha1, gamma2 GABA(A) receptor subunit genes associated to a rat nonpreferring ethanol phenotype.

Brain research. Molecular brain research - 20 Feb 2003

Congeddu Elena, Saba Luisella, Porcella Anna, Sanna Angela, Marchese Giorgio, Lobina Carla, Gessa Gian Luigi, Pani Luca

Abstract excerpt

Recent preclinical and clinical studies have indicated a possible involvement of the genes encoding for the GABA(A) receptor subunits alpha6, beta2, alpha1 and gamma2 in the genetic susceptibility to alcohol abuse. We have recently found an (R) to (Q) mutation in codon 100 of the alpha6 GABA(A) subunit, that segregated in a rat line selectively bred for its voluntary ethanol aversion, Sardinian alcohol...

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PMID: 12591165
DOI: 10.1016/s0169-328x(02)00660-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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