Article
AA and ANA rats exhibit the R100Q mutation in the GABAA receptor alpha 6 subunit.
Alcohol (Fayetteville, N.Y.) - 1 Jan 2000
Carr Lucinda G, Spence John P, Peter Eriksson C J, Lumeng Lawrence, Li Ting-Kai
Abstract excerpt
The R100Q mutation in the gamma-aminobutyric acid type A (GABA(A)) receptor alpha(6) subunit was previously identified in Sardinian alcohol-preferring (sP) and Sardinian alcohol-nonpreferring (sNP) rats as a candidate gene influencing alcohol preference and sensitivity. The purpose of the current study was to determine to what extent this mutation and alcohol preference observed in the sP and sNP lines was...
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