Article
RLF2, a subunit of yeast chromatin assembly factor-I, is required for telomeric chromatin function in vivo.
Genes & development - 1 Feb 1997
Enomoto S, McCune-Zierath P D, Gerami-Nejad M, Sanders M A, Berman J
Abstract excerpt
In the yeast Saccharomyces cerevisiae, telomere repeat DNA is assembled into a specialized heterochromatin-like complex that silences the transcription of adjacent genes. The general DNA-binding protein Rap1p binds telomere DNA repeats, contributes to telomere length control and to telomeric sile...
Topics
- Cell Nucleus
- Chromatin
- Chromatin Assembly Factor-1
- Chromosomal Proteins, Non-Histone
- Chromosomes, Fungal
- Cloning, Molecular
- DNA, Fungal
- DNA-Binding Proteins
- Escherichia coli
- Gene Expression Regulation, Fungal
- Genes, Fungal
- In Situ Hybridization, Fluorescence
- Mutation
- Promoter Regions, Genetic