Article
RLF2, a subunit of yeast chromatin assembly factor-I, is required for telomeric chromatin function in vivo.
Genes & development - 1 Feb 1997
Enomoto S, McCune-Zierath P D, Gerami-Nejad M, Sanders M A, Berman J
Abstract excerpt
In the yeast Saccharomyces cerevisiae, telomere repeat DNA is assembled into a specialized heterochromatin-like complex that silences the transcription of adjacent genes. The general DNA-binding protein Rap1p binds telomere DNA repeats, contributes to telomere length control and to telomeric silencing, and is a major component of telomeric chromatin. We identified Rap1p localization factor 2 (RLF2) in a screen...
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