Article
Structural analysis of Bacillus subtilis SPP1 phage helicase loader protein G39P.
The Journal of biological chemistry - 25 Apr 2003
Bailey Scott, Sedelnikova Svetlana E, Mesa Pablo, Ayora Sylvia, Waltho Jon P, Ashcroft Alison E, Baron Andrew J, Alonso Juan C, Rafferty John B
Abstract excerpt
The Bacillus subtilis SPP1 phage-encoded protein G39P is a loader and inhibitor of the phage G40P replicative helicase involved in the initiation of DNA replication. We have carried out a full x-ray crystallographic and preliminary NMR analysis of G39P and functional studies of the protein, including assays for helicase binding by a number of truncated mutant forms, in an effort to improve our understanding of...
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