Article
Residues within the B' motif are critical for DNA binding by the superfamily 3 helicase Rep40 of adeno-associated virus type 2.
The Journal of biological chemistry - 26 Nov 2004
Yoon-Robarts Miran, Blouin Amanda G, Bleker Svenja, Kleinschmidt Jürgen A, Aggarwal Aneel K, Escalante Carlos R, Linden R Michael
Abstract excerpt
We have recently published the crystal structure of the adeno-associated virus type 2 superfamily 3 (SF3) helicase Rep40. Although based on its biochemical properties it is unlikely that Rep40 plays a central role as a replicative helicase the involvement of this motor protein in DNA packaging has recently been demonstrated. Here we focused our attention on residues that fall within and adjacent to the B' motif...
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