Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of Histone Methyltransferase G9a in CpG Methylation of the Prader-Willi Syndrome Imprinting Center

1 Apr 2003

Abstract excerpt

Imprinted genes in mammals are often located in clusters whose imprinting is subject to long range regulation by cis-acting sequences known as imprinting centers (ICs). The mechanisms by which these ICs exert their effects is unknown. The Prader-Willi syndrome IC (PWS-IC) on human chromosome 15 and mouse chromosome 7 regulates imprinted gene expression bidirectionally within an approximately 2-megabase region and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Genetic Syndromes and Imprinting
Share to Prenatal Screening and Diagnostics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12586828
DOI: 10.1074/jbc.m211753200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of Histone Methyltransferase G9a in CpG Methylation of the Prader-Willi Syndrome Imprinting CenterPMID 12586828Read ↗

Mechanism of EHMT2-mediated genomic imprinting associated with Prader-Willi syndromeSemantic proximity Read ↗

Parent-specific complementary patterns of histone H3 lysine 9 and H3 lysine 4 methylation at the Prader-Willi syndrome imprinting center.Semantic proximity Read ↗

Mechanisms of activation of the paternally expressed genes by the Prader-Willi imprinting center in the Prader-Willi/Angelman syndromes domainsSemantic proximity Read ↗

A new deletion refines the boundaries of the murine Prader-Willi syndrome imprinting center.Semantic proximity Read ↗

An unexpected function of the Prader-Willi syndrome imprinting center in maternal imprinting in mice.Semantic proximity Read ↗

Imprinting in Prader-Willi and Angelman syndromes.Semantic proximity Read ↗

Activation of the imprinted Prader-Willi Syndrome locus by CRISPR-based epigenome editingSemantic proximity Read ↗

Towards a molecular understandingof Prader-Willi and Angelman syndromesSemantic proximity Read ↗

Activation of the imprinted Prader-Willi syndrome locus by CRISPR-based epigenome editingSemantic proximity Read ↗

Targeting the histone methyltransferase G9a activates imprinted genes and improves survival of a mouse model of Prader–Willi syndromeSemantic proximity Read ↗

Structure and function of the human chromosome 15 imprinting center.Semantic proximity Read ↗

The Prader-Willi syndrome imprinting center activates the paternally expressed murine Ube3a antisense transcript but represses paternal Ube3a.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.