Article
Imprinting in Prader-Willi and Angelman syndromes.
Trends in genetics : TIG - 1 May 1998
Nicholls R D, Saitoh S, Horsthemke B
Abstract excerpt
Imprinted genes are marked in the germline and retain molecular memory of their parental origin, resulting in allelic expression differences during development. Abnormalities in imprinted inheritance occur in several genetic diseases and cancer, and are exemplified by the diverse genetic defects...
Topics
- Angelman Syndrome
- Animals
- Biological Evolution
- Conserved Sequence
- Genomic Imprinting
- Humans
- Ligases
- Mice
- Mutation
- Prader-Willi Syndrome
- Ubiquitin-Protein Ligases