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Article

An unexpected function of the Prader-Willi syndrome imprinting center in maternal imprinting in mice.

PloS one - 1 Jan 2012

Wu Mei-Yi, Jiang Ming, Zhai Xiaodong, Beaudet Arthur L, Wu Ray-Chang

Abstract excerpt

Genomic imprinting is a phenomenon that some genes are expressed differentially according to the parent of origin. Prader-Willi syndrome (PWS) and Angelman syndrome (AS) are neurobehavioral disorders caused by deficiency of imprinted gene expression from paternal and maternal chromosome 15q11-q13, respectively. Imprinted genes at the PWS/AS domain are regulated through a bipartite imprinting center, the PWS-IC...

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Identifiers

PMID: 22496793
DOI: 10.1371/journal.pone.0034348
PMCID: PMC3319576

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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