Article

Mechanism of EHMT2-mediated genomic imprinting associated with Prader-Willi syndrome

2024-07-03

Abstract excerpt

<title>Abstract</title> <p>Prader-Willi Syndrome (PWS) is caused by loss of expression of paternally expressed genes in the human 15q11.2-q13 imprinting domain. A set of imprinted genes that are active on the paternal but silenced on the maternal chromosome are intricately regulated by a bipartite imprinting center (PWS-IC) located in the PWS imprinting domain. In past work, we discovered that euchromatic histone...

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Literature Corpus work: e2bc0209-3621-514e-b186-8aafc530f2c1
DOI: 10.21203/rs.3.rs-4530649/v1

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