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Article

In vivo dimerization of types 1, 2, and 3 iodothyronine selenodeiodinases.

Endocrinology - 1 Mar 2003

Curcio-Morelli Cyntia, Gereben Balazs, Zavacki Ann Marie, Kim Brian W, Huang Stephen, Harney John W, Larsen P Reed, Bianco Antonio C

Abstract excerpt

The goal of the present investigation was to test the hypothesis that types 1, 2, and 3 iodothyronine selenodeiodinases (D1, D2, and D3) can form homodimers. The strategy included transient coexpression of wild-type (wt) deiodinases (target), and FLAG-tagged alanine or cysteine mutants (bait) in human embryonic kidney epithelial cells. SDS-PAGE of the immunoprecipitation pellet of (75)Se-labeled cell lysates...

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PMID: 12586771
DOI: 10.1210/en.2002-220960

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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