Article
Prospective analysis of DNA damage and repair markers of lung cancer risk from the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial.
Carcinogenesis - 1 Jan 2011
Sigurdson Alice J, Jones Irene M, Wei Qingyi, Wu Xifeng, Spitz Margaret R, Stram Douglas A, Gross Myron D, Huang Wen-Yi, Wang Li-E, Gu Jian, Thomas Cynthia B, Reding Douglas J, Hayes Richard B, Caporaso Neil E
Abstract excerpt
Mutagen challenge and DNA repair assays have been used in case-control studies for nearly three decades to assess human cancer risk. The findings still engender controversy because blood was drawn after cancer diagnosis so the results may be biased, a type called 'reverse causation'. We therefore used Epstein-Barr virus-transformed lymphoblastoid cell lines established from prospectively collected peripheral...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.