Article
MYO2 is not essential for viability, but is required for polarized growth and dimorphic switches in Candida albicans.
FEMS microbiology letters - 21 Jan 2003
Woo Miyoung, Lee Kyunghee, Song Kiwon
Abstract excerpt
The human fungal pathogen Candida albicans changes from a budding yeast form to a polarized hyphal form in response to various external conditions. Dimorphic switching of C. albicans has been implicated in the development of pathogenicity. Morphogenic transformation requires polarized cell growth and rearrangement of the cytoskeleton. We previously showed that myosins play key roles in the conversion from the bud...
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