Article
Aspergillus myosin-V supports polarized growth in the absence of microtubule-based transport.
PloS one - 1 Jan 2011
Zhang Jun, Tan Kaeling, Wu Xufeng, Chen Guifang, Sun Jinjin, Reck-Peterson Samara L, Hammer John A, Xiang Xin
Abstract excerpt
In the filamentous fungus Aspergillus nidulans, both microtubules and actin filaments are important for polarized growth at the hyphal tip. Less clear is how different microtubule-based and actin-based motors work together to support this growth. Here we examined the role of myosin-V (MYOV) in hyphal growth. MYOV-depleted cells form elongated hyphae, but the rate of hyphal elongation is significantly reduced. In...
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