Article
CDK-dependent phosphorylation of Mob2 is essential for hyphal development in Candida albicans.
Molecular biology of the cell - 15 Jul 2011
Gutiérrez-Escribano Pilar, González-Novo Alberto, Suárez M Belén, Li Chang-Run, Wang Yue, de Aldana Carlos R Vázquez, Correa-Bordes Jaime
Abstract excerpt
Nuclear Dbf2-related (NDR) protein kinases are essential components of regulatory pathways involved in cell morphogenesis, cell cycle control, and viability in eukaryotic cells. For their activity and function, these kinases require interaction with Mob proteins. However, little is known about how the Mob proteins are regulated. In Candida albicans, the cyclin-dependent kinase (CDK) Cdc28 and the NDR kinase Cbk1...
Topics
- Amino Acid Sequence
- Candida albicans
- Cell Cycle
- Cell Cycle Proteins
- Cyclin-Dependent Kinases
- Fungal Proteins
- Hyphae
- Molecular Sequence Data
- Mutation
- Phosphorylation
- Sequence Homology, Amino Acid
- Signal Transduction