Article
The mitotic cyclins Clb2p and Clb4p affect morphogenesis in Candida albicans.
Molecular biology of the cell - 1 Jul 2005
Bensen Eric S, Clemente-Blanco Andres, Finley Kenneth R, Correa-Bordes Jaime, Berman Judith
Abstract excerpt
The ability of Candida albicans to switch cellular morphologies is crucial for its ability to cause infection. Because the cell cycle machinery participates in Saccharomyces cerevisiae filamentous growth, we characterized in detail the two C. albicans B-type cyclins, CLB2 and CLB4, to better understand the molecular mechanisms that underlie the C. albicans morphogenic switch. Both Clb2p and Clb4p levels are cell...
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