Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Contractions and expansions of CAG/CTG trinucleotide repeats occur during ectopic gene conversion in yeast, by a MUS81-independent mechanism.

Journal of molecular biology - 21 Feb 2003

Richard Guy Franck, Cyncynatus Camille, Dujon Bernard

Abstract excerpt

CAG/CTG trinucleotide repeat tracts expand and contract at a high rate during gene conversion in Saccharomyces cerevisiae. In order to characterize the mechanism responsible for such rearrangements, we built an experimental system based on the use of the rare cutter endonuclease I-SceI, to study the fate of trinucleotide repeat tracts during meiotic or mitotic (allelic or ectopic) gene conversion. After...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Crossing Over, Genetic
Share to Endonucleases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Conversion

Share to Genes, Fungal

Share to Meiosis

Share to Saccharomyces cerevisiae

Share to Saccharomyces cerevisiae Proteins

Share to Trinucleotide Repeats

Source

Identifiers

PMID: 12581639
DOI: 10.1016/s0022-2836(02)01405-5

Genes

MUS81

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Contractions and expansions of CAG/CTG trinucleotide repeats occur during ectopic gene conversion in yeast, by a MUS81-independent mechanism.PMID 12581639Read ↗

Highly specific contractions of a single CAG/CTG trinucleotide repeat by TALEN in yeast.Semantic proximity Read ↗

Double-strand break repair can lead to high frequencies of deletions within short CAG/CTG trinucleotide repeats.Semantic proximity Read ↗

Recombination between retrotransposons as a source of chromosome rearrangements in the yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

Resection and repair of a Cas9 double-strand break at CTG trinucleotide repeats induces local and extensive chromosomal rearrangementsSemantic proximity Read ↗

Intrachromosomal Recombination in Yeast.Semantic proximity Read ↗

Mitotic recombination in yeast: elements controlling its incidence.Semantic proximity Read ↗

Mismatch repair blocks expansions of interrupted trinucleotide repeats in yeast.Semantic proximity Read ↗

Fine-resolution mapping of spontaneous and double-strand break-induced gene conversion tracts in Saccharomyces cerevisiae reveals reversible mitotic conversion polarity.Semantic proximity Read ↗

The stabilization of repetitive tracts of DNA by variant repeats requires a functional DNA mismatch repair system.Semantic proximity Read ↗

Instability of CAG and CTG trinucleotide repeats in Saccharomyces cerevisiae.Semantic proximity Read ↗

Gene conversion plays the major role in controlling the stability of large tandem repeats in yeast.Semantic proximity Read ↗

The role of double-strand break-induced allelic homologous recombination in somatic plant cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.