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Article

Homocysteine, MTHFR 677C→T polymorphism, and risk of ischemic stroke: Results of a meta-analysis

11 Feb 2003

Abstract excerpt

Background: Data are conflicting concerning risk for ischemic stroke associated with hyperhomocyst(e)inemia (hyper-Hcy) and a common polymorphism in the gene encoding 5,10-methylenetetrahydrofolate reductase (MTHFR 677C→T), which predisposes to hyper-Hcy in vivo. Methods: Search of MEDLINE, Science Citation Index, and abstracts of conference proceedings revealed relevant articles. Exposure was defined as follows:...

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Identifiers

PMID: 12578952
DOI: 10.1212/wnl.60.3.526

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Homocysteine, MTHFR 677C→T polymorphism, and risk of ischemic stroke: Results of a meta-analysisPMID 12578952Read ↗

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