Article
Angiotensinogen gene knockout delays and attenuates cold-induced hypertension.
Hypertension (Dallas, Tex. : 1979) - 1 Feb 2003
Sun Zhongjie, Cade Robert, Zhang Zhonge, Alouidor James, Van Huong
Abstract excerpt
The aim of the present study was to assess our hypothesis that the renin-angiotensin system (RAS) is responsible for cold-induced hypertension and cardiac hypertrophy. Two groups of wild-type (WT) mice and 2 groups of angiotensinogen gene knockout (Agt-KO) mice (6 per group) were used. After blood pressures (BP) of the four groups were measured 3 times at room temperature (25 degrees C), 1 WT and 1 Agt-KO group...
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