Article
Renal baroreceptor-stimulated renin in the eNOS knockout mouse.
American journal of physiology. Renal physiology - 1 Jan 2002
Beierwaltes William H, Potter D'Anna L, Shesely Edward G
Abstract excerpt
The role of endothelium-derived nitric oxide (NO) in renal baroreceptor stimulation of renin was tested comparing endothelial nitric oxide synthase (eNOS)-deficient mice with C57BL/6J (C57) controls. We measured blood pressure, renal blood flow (RBF), and plasma renin concentration (PRC) in Inactin-anesthetized mice. Blood pressure in eNOS knockout mice was higher than in controls (100 +/- 3 vs. 86 +/- 1 mmHg,...
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