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Article

Association study of a functional catechol-O-methyltransferase-gene polymorphism and cognitive function in healthy females.

Neuroscience letters - 27 Feb 2003

Tsai Shih Jen, Yu Younger W-Y, Chen Tai Jui, Chen Jen Yeu, Liou Ying Jay, Chen Ming Chao, Hong Chen Jee

Abstract excerpt

Using the Wisconsin Card Sorting Test, it has been determined, that the catechol-O-methyltransferase (COMT) Val158Met genetic polymorphism, a functional polymorphism that may affect dopamine metabolism, is associated with prefrontal cognitive function. This study of a cohort of 120 healthy young Chinese females attempted to utilize P300 event-related potentials to replicate this finding and to test the...

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Identifiers

PMID: 12566168
DOI: 10.1016/s0304-3940(02)01396-4

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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