Article
The kic1 kinase of schizosaccharomyces pombe is a CLK/STY orthologue that regulates cell-cell separation.
Experimental cell research - 1 Feb 2003
Tang Zhaohua, Mandel Linda L, Yean Shyue-Lee, Lin Cindy X, Chen Tina, Yanagida Mitsuhiro, Lin Ren-Jang
Abstract excerpt
The CLK/STY kinases are a family of dual-specificity protein kinases implicated in the regulation of cellular growth and differentiation. Some of the kinases in the family are shown to phosphorylate serine-arginine-rich splicing factors and to regulate pre-mRNA splicing. However, the actual cellular mechanism that regulates cell growth, differentiation, and development by CLK/STY remains unclear. Here we show...
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