Article
Identification of a novel casein kinase-1 homolog in fission yeast Schizosaccharomyces pombe.
Gene - 3 Jul 1998
Kitamura K, Yamashita I
Abstract excerpt
Fission yeast cells lacking either the ste9+- or rum1+ function cannot enter the cell differentiation pathway upon nutritional starvation. Sterility in both mutants is suppressed by the srs1-S41 mutation. A gene encoding a novel casein kinase-1 (CK1) isoform, cki3+, was isolated as a high-copy-number suppressor gene of the srs1 mutation. Cki3 protein is structurally more related to the Cki/Yck subfamily proteins...
Topics
- Amino Acid Sequence
- Base Sequence
- Casein Kinases
- Cloning, Molecular
- DNA Primers
- DNA, Fungal
- Gene Deletion
- Genes, Fungal
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Mutation
- Phenotype