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Article

Kep1 interacts genetically with dredd/caspase-8, and kep1 mutants alter the balance of dredd isoforms.

Proceedings of the National Academy of Sciences of the United States of America - 18 Feb 2003

Di Fruscio Marco, Styhler Sylvia, Wikholm Eva, Boulanger Marie-Chloe, Lasko Paul, Richard Stephane

Abstract excerpt

The Drosophila kep1 gene encodes an RNA binding protein related to the murine QUAKING apoptotic inducer. We have previously shown that kep1 can induce apoptosis when transfected into different cell lines. To better define the role of Kep1 in apoptosis, we generated kep1 null flies. These flies we...

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Identifiers

PMID: 12563030
DOI: 10.1073/pnas.0236048100
PMCID: PMC149916

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12563030-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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