Article
Cell death inhibiting RNA (CDIR) derived from a 3'-untranslated region binds AUF1 and heat shock protein 27.
The Journal of biological chemistry - 6 Dec 2002
Shchors Ksenya, Yehiely Fruma, Kular Rupinder K, Kotlo Kumar U, Brewer Gary, Deiss Louis P
Abstract excerpt
Regulators of programmed cell death were previously identified using a technical knockout genetic screen. Among the elements that inhibited interferon-gamma-induced apoptosis of HeLa cells was a 441-nucleotide fragment derived from the 3'-untranslated region (UTR) of KIAA0425, a gene of unknown function. This fragment was termed cell death inhibiting RNA (CDIR). Deletion and mutation analyses of CDIR were...
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