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Article

Vimentin intermediate filament reorganization by Cdc42: involvement of PAK and p70 S6 kinase.

European journal of cell biology - 1 Dec 2002

Chan Wing, Kozma Robert, Yasui Yoshihiro, Inagaki Masaki, Leung Thomas, Manser Ed, Lim Louis

Abstract excerpt

Rho family GTPases play a major role in actin cytoskeleton reorganization. Recent studies have shown that the activation of Rho family GTPases also induces collapse of the vimentin intermediate filament (IF) network in fibroblasts. Here, we report that Cdc42V12 induces the reorganization of vimentin IFs in Hela cells, and such reorganization is independent of actin and microtubule status. We analyzed the...

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Source

Identifiers

PMID: 12553669
DOI: 10.1078/0171-9335-00281

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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