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Article

ILK mediates actin filament rearrangements and cell migration and invasion through PI3K/Akt/Rac1 signaling.

Oncogene - 28 Apr 2005

Qian Yong, Zhong Xiaosong, Flynn Daniel C, Zheng Jenny Z, Qiao Meng, Wu Chuanyue, Dedhar Shoukat, Shi Xianglin, Jiang Bing-Hua

Abstract excerpt

One of the hallmarks of integrin signaling is an increase in cell migration and invasion, both of which are associated with actin filament rearrangements. Integrin-linked kinase (ILK) is a cytoplasmic effector of integrin receptors. ILK is known to be involved in multiple cellular functions. Howe...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15735674
DOI: 10.1038/sj.onc.1208525

Genes

ILK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15735674-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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ILK mediates actin filament rearrangements and cell migration and invasion through PI3K/Akt/Rac1 signaling.PMID 15735674Read ↗

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