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Article

Divergent distribution of HIV-1 drug-resistant variants on and off antiretroviral therapy.

Antiviral therapy - 1 Dec 2002

Venturi Giulietto, Romano Laura, Carli Tiziana, Corsi Paola, Pippi Luigi, Valensin Pier E, Zazzi Maurizio

Abstract excerpt

OBJECTIVE: To investigate the distribution of drug-resistant HIV-1 variants in plasma RNA and peripheral blood monuclear cell (PBMC) DNA at treatment failure while on therapy and after stopping therapy. DESIGN: Fifty-eight patients failing their first highly active antiretroviral treatment while on therapy and 50 patients after a median of 18.6 weeks after treatment interruption following multiple treatment...

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PMID: 12553478

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