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Article

HIV-1-resistant strains during 8-week on 8-week off intermittent therapy and their effect on CD4+ T-cell counts and antiviral response.

Antiviral therapy - 1 Jan 2008

Izopet Jacques, Marchou Bruno, Charreau Isabelle, Sauné Karine, Tangre Philippe, Molina Jean-Michel, Aboulker Jean-Pierre

Abstract excerpt

BACKGROUND: We aimed here to study drug-associated HIV resistance mutations in peripheral blood mononuclear cells (PBMC) and plasma during intermittent therapy. METHODS: A substudy of 86 patients randomized to the intermittent treatment arm (8-week on/8-week off) of the ANRS 106 Window trial. HIV reverse transcriptase and protease genes were sequenced and resistance mutations identified according to the...

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Identifiers

PMID: 18672532

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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