Article
HIV-1 drug resistance genotypic profiles in children with undetectable plasma viremia during antiretroviral therapy.
The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases - 1 Jan 2000
Angelis Daniela Souza Araújo de, Tateno Adriana Fumie, Diaz Ricardo Sobhie, Succi Regina Célia de Menezes, Pannuti Claudio Sergio, Gouvea Aida de Fátima Barbosa, Machado Daisy Maria
Abstract excerpt
Treatment of HIV-1 infection with highly active antiretroviral therapy has led to sustained viral suppression in the plasma in a large number of children. However, studies have suggested that the integrated provirus in resting CD4+ T lymphocytes could be a source of reactivatable virus and maintain drug-resistant virus. We evaluated the resistance-related mutations in children receiving antiretroviral therapy...
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