Article
Determinants of HIV drug resistance mutations in plasma virus after treatment interruption.
AIDS (London, England) - 2 Dec 2005
Chilton Daniella, Dervisevic Samir, Pillay Deenan, Rider Andrew, Copas Andrew, Miller Rob F, Edwards Simon G
Abstract excerpt
This study examines the utility of resistance testing during treatment interruption, making comparisons with the current IAS guidelines. A total of 188/1279 tests (14%) were performed during treatment interruption; 69/188 tests (36.7%) demonstrated key mutations. Time off therapy and the total number of previous drugs were both significantly associated with the presence of mutations. We conclude that resistance...
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