A model for tumor suppression using H-1 parvovirus.

doi:10.1073/pnas.90.18.8702

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Article

A model for tumor suppression using H-1 parvovirus.

Proceedings of the National Academy of Sciences of the United States of America - 15 Sept 1993

Telerman A, Tuynder M, Dupressoir T, Robaye B, Sigaux F, Shaulian E, Oren M, Rommelaere J, Amson R

Abstract excerpt

A model system is proposed to investigate, at the molecular level, the pathways of tumor suppression. As a tool for the selection of cells with a suppressed phenotype, we used the H-1 parvovirus that preferentially kills various neoplastic cells. From the human K562 leukemia cells, we isolated a...

Topics

Antigens, CD
Base Sequence
Blotting, Western
Cell Survival
Clone Cells
DNA, Viral
Electrophoresis, Gel, Two-Dimensional
Genes, Tumor Suppressor
Genes, p53
Humans
Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Methionine

Molecular Sequence Data

Molecular Weight

Neoplasm Proteins

Oligodeoxyribonucleotides

Parvoviridae

Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 8378352
DOI: 10.1073/pnas.90.18.8702
PMCID: PMC47426

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8378352-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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