Article
Linkage and association with structural relationships.
Advances in genetics - 1 Jan 2001
Province M A
Abstract excerpt
The use of structural equations (path analysis) provides an alternative, equivalent formulation to variance components models. Instead of partitioning the variance, we focus on modeling the underlying random variables themselves through a system of linear, mixed model, regression equations. A few specific examples of genetic path models for linkage and association (linkage disequilibrium) are discussed. This...
Topics
- Chromosome Mapping
- Genetic Diseases, Inborn
- Genetic Linkage
- Humans
- Models, Genetic
- Models, Theoretical
- Nuclear Family
- Phenotype