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Article

Effect of atorvastatin on adhesive phenotype of human endothelial cells activated by tumor necrosis factor alpha.

Journal of cardiovascular pharmacology - 1 Feb 2003

Bernot Denis, Benoliel Anne-Marie, Peiretti Franck, Lopez Sophie, Bonardo Bernadette, Bongrand Pierre, Juhan-Vague Irène, Nalbone Gilles

Abstract excerpt

We studied the effect of atorvastatin on the adhesive phenotype of human endothelial cells (HUVEC) stimulated by tumor necrosis factor (TNF)-alpha. Surface expression of adhesion molecules on HUVEC was examined by flow cytometry and confocal microscopy, and adhesion of monocytes (human THP-1 cell line) was measured in vitro under flow conditions. In TNF-alpha-activated HUVEC, atorvastatin significantly enhanced...

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Identifiers

PMID: 12548094
DOI: 10.1097/00005344-200302000-00022

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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