Article
Atorvastatin reduces the proadhesive and prothrombotic endothelial cell phenotype induced by cocaine and plasma from cocaine consumers in vitro.
Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 2014
Sáez Claudia G, Pereira-Flores Karla, Ebensperger Roberto, Panes Olga, Massardo Teresa, Hidalgo Patricia, Mezzano Diego, Pereira Jaime
Abstract excerpt
OBJECTIVE: Cocaine consumption is a risk factor for vascular ischemic complications. Although endothelial dysfunction and accelerated atherosclerosis have been observed in cocaine consumers, the mechanisms underlying their pathogenesis are not fully understood. This study aimed at identifying the effects of atorvastatin in relation to a proadhesive and prothrombotic phenotype induced by cocaine and plasma from...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.